NSC 95397
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-108543-50 mg |
| CAS # | 93718-83-3 |
| Pricing | 50 mg, USD $450.0 |
| Biological Activity | NSC 95397 is a potent, selective Cdc25 dual specificity phosphatase inhibitor (Ki=32 nM (Cdc25A), 96 nM (Cdc25B), 40 nM (Cdc25C); IC50=22.3 nM (human Cdc25A), 56.9 nM (human Cdc25C), 125 nM (Cdc25B))[1]. NSC 95397 inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) and suppresses proliferation and induces apoptosis in colon cancer cells through MKP-1 and ERK1/2 pathway[2]. |
| Purity | ≥99.0% |
| MWt | 310.39 |
| Formula | C₁₄H₁₄O₄S₂ |