MRK-016
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-100370-10 mM * 1 mL |
| CAS # | 342652-67-9 |
| Pricing | 10 mM * 1 mL, USD $132.0 |
| Biological Activity | MRK-016 is a selective, orally bioavailable inverse agonist of GABAA α5 receptor, with an EC50 of 3 nM for GABAA α5, and Kis of 0.83, 0.85, 0.77 and 1.4 nM for human GABAA α1β3γ2, GABAA α2β3γ2, GABAA α3β3γ2, and GABAA α5β3γ2, respectively; MRK-016 also readily penetrates the CNS. |
| Purity | 99.27% |
| MWt | 368.39 |
| Formula | C₁₇H₂₀N₈O₂ |