Vardenafil
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-B0442 |
| CAS # | 224785-90-4 |
| Pricing | inquire |
| Biological Activity | Vardenafil is a selective, orally active, potent inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil shows selectivity over PDE1 (180 nM), PDE6 (11 nM), PDE2, PDE3, and PDE4 (>1000 nM). Vardenafil competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil can be used for the research of erectile dysfunction[1][2]. |
| MWt | 488.6 |
| Formula | C₂₃H₃₂N₆O₄S |