Theliatinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-104066-10 mM * 1 mL |
| CAS # | 1353644-70-8 |
| Pricing | 10 mM * 1 mL, USD $234.0 |
| Synonyms | HMPL-309 |
| MWt | 442.51 |
| Formula | C₂₅H₂₆N₆O₂ |
| Biological Activity | Theliatinib (HMPL-309) is a potent, ATP-competitive, orally active and highly selective EGFR inhibitor with a Ki of 0.05 nM and an IC50 of 3 nM. Theliatinib has an IC50 of 22 nM for EGFR T790M/L858R mutant. Theliatinib shows >50-fold selectivity for EGFR than other kinases. Anti-tumor activity[1]. |
| Purity | 99.88% |