Fatostatin hydrobromide
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-14452A-25 mg |
| CAS # | 298197-04-3 |
| Pricing | 25 mg, USD $145.0 |
| Synonyms | 125B11 hydrobromide |
| MWt | 375.33 |
| Formula | C₁₈H₁₉BrN₂S |
| Biological Activity | Fatostatin hydrobromide (125B11 hydrobromide), a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2. Fatostatin hydrobromide binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin hydrobromide decreases the transcription of lipogenic genes in cells. Fatostatin hydrobromide possesses antitumor properties, and lowers hyperglycemia in ob/ob mice[1][2]. |
| Purity | 99.61% |