NSC697923

Supplier MedChemExpress
Product # HY-13811-50 mg
CAS # 343351-67-7
Pricing 50 mg, USD $250.0
Biological Activity NSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-κB signaling. Antitumor activity[1][2].
MWt 267.26
Formula C₁₁H₉NO₅S
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