Tyrphostin AG 879
Supplier | MedChemExpress |
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Product # | HY-20878-10 mM * 1 mL |
CAS # | 148741-30-4 |
Pricing | 10 mM * 1 mL, USD $55.0 |
Synonyms | AG 879 |
MWt | 316.46 |
Formula | C₁₈H₂₄N₂OS |
Biological Activity | Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation (IC50 of 10 μM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective ErbB2 tyrosine kinase inhibitor with an IC50 of 1 μM, and has at least 500-fold higher selectivity to ErbB2 than EGFR. Tyrphostin AG 879 has anticancer activity[1][2][3]. |
Purity | 99.54% |