G907

Supplier MedChemExpress
Product # HY-125176-10 mg
CAS # 2244035-16-1
Pricing 10 mg, USD $980.0
Biological Activity G907 is a selective small-molecule antagonist of ATP-binding cassette (ABC) transporter, MsbA. It inhibits purified E. coli MsbA in amphipols with an IC50 of 18 nM. G907 traps MsbA in an inward-facing, lipopolysaccharide-bound conformation by wedging into an architecturally conserved transmembrane pocket. Bactericidal activity[1].
Purity 98.34%
MWt 433.93
Formula C₂₆H₂₄ClNO₃
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