G907
Supplier | MedChemExpress |
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Product # | HY-125176-10 mg |
CAS # | 2244035-16-1 |
Pricing | 10 mg, USD $980.0 |
Biological Activity | G907 is a selective small-molecule antagonist of ATP-binding cassette (ABC) transporter, MsbA. It inhibits purified E. coli MsbA in amphipols with an IC50 of 18 nM. G907 traps MsbA in an inward-facing, lipopolysaccharide-bound conformation by wedging into an architecturally conserved transmembrane pocket. Bactericidal activity[1]. |
Purity | 98.34% |
MWt | 433.93 |
Formula | C₂₆H₂₄ClNO₃ |