Human Anti-DR5 Recombinant Antibody (clone Apomab)
Recombinant Human Antibody (Apomab) is capable of binding to DR5, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-DR5 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-DR5 proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody induces tumor cell apoptosis through DR5 and investigated the structural features of its interaction with DR5.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABL-453 |
| Pricing | Inquiry |
| Host | Human |
| Target | DR5 |
| Species Reactivity | Human |
| Type | Human IgG |
| Applications | FC, ELISA |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |