Firibastat
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-109058-10 mM * 1 mL |
| CAS # | 648927-86-0 |
| Pricing | 10 mM * 1 mL, USD $132.0 |
| Synonyms | QGC001; RB150 |
| MWt | 368.51 |
| Formula | C₈H₂₀N₂O₆S₄ |
| Biological Activity | Firibastat (QGC001), an orally active brain penetrating prodrug of EC33, is a first-in-class brain aminopeptidase A (APA) inhibitor (Ki=200 nM). Firibastat selectively and specifically inhibits conversion of brain angiotensin-II into angiotensin-III and decreases blood pressure in hypertensive rats[1][2]. |
| Purity | ≥98.0% |