DC0-NH2
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-129379-5 mg |
| CAS # | 615538-51-7 |
| Pricing | 5 mg, USD $980.0 |
| Biological Activity | DC0-NH2 is an effector moiety for ADC and a simplified analog of DC1 with better stability. DC0-NH2 is about 1000-fold more cytotoxic than commonly used anticancer drugs (ex. Doxorubicin). DC0-NH2 can bind to the minor groove of DNA, followed by alkylation of adenine residues by its propabenzindole (CBI) component[1]. |
| MWt | 550.01 |
| Formula | C₃₁H₂₄ClN₅O₃ |