AKT-IN-3
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-126257 |
| CAS # | 2374740-21-1 |
| Pricing | inquire |
| Biological Activity | AKT-IN-3 (compound E22) is a potent, orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK. AKT-IN-3 (compound E22) induces apoptosis and inhibits metastasis of cancer cells[1]. |
| MWt | 526.36 |
| Formula | C₂₃H₂₃Cl₂F₂N₅O₃ |