NSC 95397

Supplier MedChemExpress
Product # HY-108543-10 mg
CAS # 93718-83-3
Pricing 10 mg, USD $110.0
Biological Activity NSC 95397 is a potent, selective Cdc25 dual specificity phosphatase inhibitor (Ki=32 nM (Cdc25A), 96 nM (Cdc25B), 40 nM (Cdc25C); IC50=22.3 nM (human Cdc25A), 56.9 nM (human Cdc25C), 125 nM (Cdc25B))[1]. NSC 95397 inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) and suppresses proliferation and induces apoptosis in colon cancer cells through MKP-1 and ERK1/2 pathway[2].
Purity ≥99.0%
MWt 310.39
Formula C₁₄H₁₄O₄S₂
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