Sunitinib Malate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10255-10 mM * 1 mL |
| CAS # | 341031-54-7 |
| Pricing | 10 mM * 1 mL, USD $715.0 |
| Synonyms | SU 11248 Malate |
| MWt | 532.56 |
| Formula | C₂₆H₃₃FN₄O₇ |
| Biological Activity | Sunitinib Malate (SU 11248 Malate) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively[1]. Sunitinib Malate, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation[2]. |
| Purity | ≥99.0% |