BD1063 HCl
BD1063 is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 9 ± 1 nM for the sigma-1 receptor and more than 49 times selectivity over the sigma-2 receptor. Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with BD1063 significantly decreases the convulsivity and lethality of cocaine. In other animal studies, BD1063 blocks the effects of MDMA, and reduces alcohol intake in rodent models of alcoholism.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD690 |
| CAS # | 206996-13-6 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | 206996-13-6 (HCl), 150208-28-9 (free base), |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C13H20Cl4N2 |
| Molecular Weight | 346.117 |
| Elemental Analysis | C, 45.11; H, 5.82; Cl, 40.97; N, 8.09 |
| IUPAC/Chemical Name | 1-[2-(3,4-dichlorophenyl)ethyl]-4-methyl-piperazine, dihydrochloride |
| InChi Key | NXFDBTLQOARIMH-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C13H18Cl2N2.2ClH/c1-16-6-8-17(9-7-16)5-4-11-2-3-12(14)13(15)10-11;;/h2-3,10H,4-9H2,1H3;2*1H |
| SMILES Code | CN1CCN(CCC2=CC=C(Cl)C(Cl)=C2)CC1.[H]Cl.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |