| Supplier |
Creative Peptides |
| Product # |
10-101-324 |
| CAS # |
1094-61-7 |
| Pricing |
Inquire
|
| Synonyms |
β-NMN, β-Nicotinamide ribose monophosphate, NMN
|
| MolecularFormula |
C11H15N2O8P
|
| MolecularWeight |
334.2
|
| Explanation |
β-Nicotinamide Mononucleotide (β-NMN) is an intermediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Nicotinamide phosphoribosyltransferase (Nampt) catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to generate β-NMN, which is subsequently converted to NAD+ by β-NMN adenyltransferase. β-NMN has several beneficial pharmacological activities. Mostly mediated by its involvement in NAD+ biosynthesis, including its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity.
|
| ChemicalName |
3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-pyridinium, inner salt
|
| Application |
β-Nicotinamide mononucleotide (β-NMN), a key β-NAD+ intermediate, has been shown to enhance β-NAD+ biosynthesis and ameliorate various pathologies in mouse disease models.
|
| Appearance |
White to off-white powder
|
| Purity |
≥ 98% (HPLC)
|