N-(4-fluorophenyl)-N-(4-((7-hydroxy-6-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide
It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.
| Supplier | BOC Sciences |
|---|---|
| Product # | 1628530-47-1 |
| Pricing | Inquire |
| Cas | 1628530-47-1 |
| Molecular Weight | 487.48 |
| Molecular Formula | C27H22FN3O5 |
| Canonical SMILES | COC1=CC2=NC=CC(=C2C=C1O)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F |