AS601245
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-11010-10 mg |
| CAS # | 345987-15-7 |
| Pricing | 10 mg, USD $210.0 |
| Biological Activity | AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases. Neuroprotective properties[1][2]. |
| Purity | 98.70% |
| MWt | 372.45 |
| Formula | C₂₀H₁₆N₆S |