Nutlin-3a
Supplier | MedChemExpress |
---|---|
Product # | HY-10029-5 mg |
CAS # | 675576-98-4 |
Pricing | 5 mg, USD $132.0 |
Biological Activity | Nutlin-3a, an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). Nutlin-3a inhibits MDM2-p53 interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. Nutlin-3a has the potential for the study of TP53 wild-type ovarian carcinomas[1][2]. |
Purity | 98.07% |
MWt | 581.49 |
Formula | C₃₀H₃₀Cl₂N₄O₄ |