L002
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-100671-10 mM * 1 mL |
| CAS # | 321695-57-2 |
| Pricing | 10 mM * 1 mL, USD $69.0 |
| Biological Activity | L002 is a potent, cell permeable, reversible and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM[1]. L002 binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain, blocks histone acetylation and p53 acetylation, and inhibits STAT3 activation[2]. L002 has the potential for hypertension‐induced cardiac hypertrophy and fibrogenesis treatment[3]. |
| Purity | 98.80% |
| MWt | 321.35 |
| Formula | C₁₅H₁₅NO₅S |