Regulator of Nonsense Transcripts 1 (UPF1) Antibody
UPF1 Antibody is a Rabbit Polyclonal antibody against UPF1. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx001282-100UL |
| Pricing | 100 µl USD $464.0 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Tested Applications | WB, IF/ICC, IP |
| UniProt Primary AC | Q92900 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |