Imatinib Impurity E
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-131275-5 mg |
| CAS # | 1365802-18-1 |
| Pricing | 5 mg, USD $350.0 |
| Biological Activity | Imatinib Impurity E is the impurity of Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively[1][2][3][4]. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV[5]. |
| MWt | 873.02 |
| Formula | C₅₂H₄₈N₁₂O₂ |