Motixafortide (BL-8040)
Motixafortide (BL-8040, BKT140, TF 14016, 4-fluorobenzoyl, 4F-benzoyl-TN14003, T140) is an antagonist of CXCR4 with IC50 of ~1 nM. BL-8040 induces the apoptosis of AML blasts by down-regulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression.
Supplier | Selleck Chemicals |
---|---|
Product # | S9665 |
Sku # | S9665-5mg |
Pricing | 5mg, $417.00 |