7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-1,2,3,4-tetrahydroquinoline
7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-1,2,3,4-tetrahydroquinoline is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.
| Supplier | BOC Sciences |
|---|---|
| Product # | BB066550 |
| Pricing | Inquire |
| Cas | 1904651-39-3 |
| Molecular Weight | 263.29 |
| Molecular Formula | C14H15F2N3 |
| Canonical SMILES | CN1C=C(C=N1)C2=C(C=C3C(=C2)CCCN3)C(F)F |