BNC-210 TFA
BNC210, also known as IW-2143, is an anxiolytic drug that acts via negative allosteric modulation of the α7-nicotinic acetylcholine receptor. It is currently being investigated for the treatment of post traumatic stress disorder. The drug has demonstrated clinically significant anxiety reduction in both animal models and in Phase I trials.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD132 |
| CAS # | 160448-56-6 (TFA) |
| Pricing | Customizable size, Inquiry |
| Synonym | BNC-210; BNC 210; BNC210; IW-2143; IW 2143; IW2143 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C19H24F3N3O5 |
| Molecular Weight | 431.4122 |
| Elemental Analysis | C, 52.90; H, 5.61; F, 13.21; N, 9.74; O, 18.54 |
| IUPAC/Chemical Name | (2S)-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid trifluoroacetic acid |
| InChi Key | GIOABCXJJDQJDM-QXGXBFBTSA-N |
| InChi Code | InChI=1S/C17H23N3O3.C2HF3O2/c1-3-10(2)15(18)16(21)20-14(17(22)23)8-11-9-19-13-7-5-4-6-12(11)13;3-2(4,5)1(6)7/h4-7,9-10,14-15,19H,3,8,18H2,1-2H3,(H,20,21)(H,22,23);(H,6,7)/t10-,14-,15-;/m0./s1 |
| SMILES Code | O=C(O)[C@@H](NC([C@@H](N)[C@@H](C)CC)=O)CC1=CNC2=C1C=CC=C2.O=C(O)C(F)(F)F |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | To be determined |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | To be determined |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |