JHU-083
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-122218-1 mg |
| CAS # | 1998725-11-3 |
| Pricing | 1 mg, USD $320.0 |
| Biological Activity | JHU-083, a prodrug of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b+ cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals[1][2]. |
| MWt | 312.36 |
| Formula | C₁₄H₂₄N₄O₄ |