iFSP1
Supplier | MedChemExpress |
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Product # | HY-136057-100 mg |
CAS # | 150651-39-1 |
Pricing | 100 mg, USD $400.0 |
Biological Activity | iFSP1 is a potent, selective and glutathione-independent inhibitor of ferroptosis suppressor protein 1 (FSP1) (AIFM2) with an EC50 of 103 nM. iFSP1 selectively induces ferroptosis in GPX4-knockout cells which overexpressed FSP1. iFSP1 is able to sensitize a variety of human cancer cell lines to the ferroptosis inducer, such as (1S,3R)-RSL3 (HY-100218A)[1]. |
Purity | 99.72% |
MWt | 323.35 |
Formula | C₂₀H₁₃N₅ |