ARCA trisodium salt
ARCA trisodium salt is a compound used in molecular biology, particularly in mRNA capping studies. ARCA stands for "Anti-Reverse Cap Analog." It's a modified nucleotide analog used to synthesize capped mRNA in vitro. In this compound, a modified guanosine molecule (commonly referred to as m7G) is attached to the 5' end of an RNA molecule in the reverse orientation, which prevents the mRNA from being degraded by exonucleases. The trisodium salt form of ARCA enhances its solubility in water, making it easier to handle in laboratory settings. ARCA trisodium salt is employed in various molecular biology applications, including the production of capped mRNA for gene expression studies, RNA vaccines, and therapeutic mRNA formulations.
Supplier | BOC Sciences |
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Product # | BRP-00469 |
Pricing | Inquire |
Cas | 400806-60-2 |
Molecular Weight | 882.41 |
Molecular Formula | C22H28N10Na3O18P3 |
Canonical SMILES | [Na].[Na].[Na].O=C1N=C(N)NC2=C1N=CN2C3OC(COP(=O)(O)OP(=O)(O)OP(=O)([O-])OCC4OC(N5C=[N+](C=6C(=O)N=C(N)NC65)C)C(O)C4OC)C(O)C3O |