Deucravacitinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-117287-10 mM * 1 mL |
| CAS # | 1609392-27-9 |
| Pricing | 10 mM * 1 mL, USD $209.0 |
| Synonyms | BMS-986165 |
| MWt | 425.46 |
| Formula | C₂₀H₁₉D₃N₈O₃ |
| Biological Activity | Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases, which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. Deucravacitinib inhibits IL-12/23 and type I IFN pathways[1][2]. |
| Purity | 99.79% |