TAK-285
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15196-10 mM * 1 mL |
| CAS # | 871026-44-7 |
| Pricing | 10 mM * 1 mL, USD $108.0 |
| Biological Activity | TAK-285 is a potent, selective, ATP-competitive and orally active HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, respectively. TAK-285 is >10-fold selectivity for HER1/2 than HER4, and less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. TAK-285 has effective antitumor activity[1]. TAK-285 can cross the blood-brain barrier (BBB)[2]. |
| MWt | 547.96 |
| Formula | C₂₆H₂₅ClF₃N₅O₃ |