Bractoppin
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-126020-5 mg |
| CAS # | 2290527-07-8 |
| Pricing | 5 mg, USD $150.0 |
| Biological Activity | Bractoppin is a potent and selective drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem(t) BRCT domain (binding IC50: 74 nM). Bractoppin diminishes BRCA1 recruitment to DNA breaks, in turn suppressing damage-induced G2 arrest and assembly of the recombinase, RAD51. Bractoppin preferentially inhibits BRCA1 tBRCT-dependent steps in the DNA damage response[1]. |
| Purity | 99.18% |
| MWt | 414.47 |
| Formula | C₂₅H₂₃FN₄O |