| Supplier |
Creative Peptides |
| Product # |
Z10-101-158 |
| CAS # |
208538-73-2 |
| Pricing |
Inquire
|
| LabelingTarget |
1, 3-beta-D-glucan synthesis
|
| Synonyms |
Funguard, FK463
|
| MolecularFormula |
C56H70N9O23SNa
|
| MolecularWeight |
1292.26
|
| Storage |
−20°C
|
| Explanation |
Micafungin is an antifungal drug that belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
|
| Application |
Formerly known as FK463, micafungin is a semisynthetic lipopeptide synthesized from a fermentation product of Coleophoma empetri that works as an antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class.
|
| Activity |
Inhibitor
|
| BiologicalActivity |
Micafungin Sodium is the sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with antifungal activity. Micafungin, like other cyclic lipopeptides, noncompetitively inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, an enzyme essential for the synthesis of the important fungal cell wall component 1,3-beta-D-glucan.
|
| AreasOfInterest |
Infection
|
| Functions |
1,3-beta-d-glucan synthase activity
|
| Disease |
- Candidiasis of the esophagus;
- Disseminated candidiasis;
- Candidal septicemia
|
| Organism |
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
|