Isofistularin-3
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-19826 |
| Pricing | inquire |
| Biological Activity | Isofistularin-3 is a direct, DNA-competitive DNMT1 inhibitor, with an IC50 of 13.5 μM. Isofistularin-3, as a DNA demethylating agent, induces cell cycle arrest and sensitization to TRAIL in cancer cells. Isofistularin-3 can be used as an ADC cytotoxin[1]. |
| MWt | 1114.01 |
| Formula | C₃₁H₃₀Br₆N₄O₁₁ |