BMS-984923
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-122559 |
| CAS # | 1375752-78-5 |
| Pricing | inquire |
| Biological Activity | BMS-984923, a potent mGluR5 silent allosteric modulator (SAM), with exquisite binding affinity (Ki = 0.6 nM), exhibits good oral bioavailability and BBB penetration. BMS-984923 potently inhibits the PrPC-mGluR5 interaction and prevents pathological Aβo signaling without affecting physiological glutamate signaling[1]. |
| MWt | 374.82 |
| Formula | C₂₂H₁₅ClN₂O₂ |