Tivantinib
Tivantinib is the first non-ATP-competitive c-Met inhibitor with Ki of 0.355 μM in a cell-free assay, little activity to Ron, and no inhibition to EGFR, InsR, PDGFRα or FGFR1/4. Tivantinib (ARQ 197) induces a G2/M arrest and apoptosis.
Supplier | Selleck Chemicals |
---|---|
Product # | S2753 |
Sku # | S2753-10mM/1mL |
Pricing | 10mM/1mL, $117.00 |