MG-132

Supplier MedChemExpress
Product # HY-13259-100 mg
CAS # 133407-82-6
Pricing 100 mg, USD $280.0
Synonyms Z-Leu-Leu-Leu-al; MG132
MWt 475.62
Formula C₂₆H₄₁N₃O₅
Biological Activity MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC50s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator[1][2][3]. MG-132 also induces apoptosis[2].
Purity ≥98.0%
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