MG-132
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13259-100 mg |
| CAS # | 133407-82-6 |
| Pricing | 100 mg, USD $280.0 |
| Synonyms | Z-Leu-Leu-Leu-al; MG132 |
| MWt | 475.62 |
| Formula | C₂₆H₄₁N₃O₅ |
| Biological Activity | MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC50s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator[1][2][3]. MG-132 also induces apoptosis[2]. |
| Purity | ≥98.0% |