CK2/ERK8-IN-1

Supplier MedChemExpress
Product # HY-135906-10 mM * 1 mL
CAS # 1085822-09-8
Pricing 10 mM * 1 mL, USD $88.0
Biological Activity CK2/ERK8-IN-1 is a dual casein kinase 2 (CK2) (Ki of 0.25 µM) and ERK8 (MAPK15, ERK7) inhibitor with IC50s of 0.50 μM. CK2/ERK8-IN-1 also binds to PIM1, HIPK2 (homeodomain-interacting protein kinase 2), and DYRK1A with Kis of 8.65 µM, 15.25 µM, and 11.9 µM, respectively. CK2/ERK8-IN-1 has pro-apoptotic efficacy[1].
Purity ≥99.0%
MWt 534.82
Formula C₁₁H₉Br₄N₃O₂
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