Hck-IN-1

Supplier MedChemExpress
Product # HY-125028-5 mg
CAS # 1473404-51-1
Pricing 5 mg, USD $350.0
Biological Activity Hck-IN-1 (compound B9), a diphenylpyrazolo compound, is a selective Nef-dependent Hck inhibitor with IC50s of 2.8 μM, >20 μM for Nef:Hck complex and Hck, respectively. Hck-IN-1 is a direct and wide HIV-1 Nef antagonists with an IC50 of 100-300 nM for wild-type HIV-1 replication. Hck-IN-1 binds pocket residue Asn126 and has anti-retroviral activity[1].
Purity ≥98.0%
MWt 402.81
Formula C₁₆H₁₁ClN₆O₃S
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