QM31
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-125018 |
| CAS # | 937735-00-7 |
| Pricing | inquire |
| Biological Activity | QM31 (SVT016426), a cytoprotective agent, is a selective inhibitor of Apaf-1. QM31 inhibits the formation of the apoptosome (IC50=7.9μM), the caspase activation complex composed by Apaf-1, cytochrome c, dATP and caspase-9. QM31 exerts mitochondrioprotective functions and interferes with the intra-S-phase DNA damage checkpoint[1][2]. |
| Synonyms | SVT016426 |
| MWt | 768.56 |
| Formula | C₃₉H₃₈Cl₄N₄O₄ |