E7820
Supplier | MedChemExpress |
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Product # | HY-14571-10 mM * 1 mL |
CAS # | 289483-69-8 |
Pricing | 10 mM * 1 mL, USD $97.0 |
Synonyms | ER68203-00 |
MWt | 336.37 |
Formula | C₁₇H₁₂N₄O₂S |
Biological Activity | E7820 (ER68203-00), an orally active aromatic sulfonamide derivative, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. E7820 inhibits rat aorta angiogenesis with an IC50 of 0.11 μg/ml. E7820 modulates α-1, α-2, α-3, and α-5 integrin mRNA expression. Antiangiogenic and antitumor activity[1][2]. |
Purity | 99.36% |