| Supplier |
CD BioSciences |
| Product # |
AMA-0183 |
| Pricing |
100 μL, Inquire
|
| Product Category |
Antibodies
|
| Application |
WB, IHC
|
| Product Usage Information Dilution |
Western Blotting (1:1000); Immunohistochemistry (1:10-1:50)
|
| Reactivity |
Human, Mouse
|
| Host |
Rabbit
|
| Source/Isotype |
Rabbit IgG
|
| Storage |
Store at -20°C.
|
| Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification.
|
| Background |
Androgens exhibit a wide range of effects on the development, maintenance and regulation of male phenotype and reproductive physiology in males. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind active testosterone (T) and dihydrotestosterone (DHT). The rates of association and dissociation of T are about 3 times more rapid than those of DHT. This difference in binding kinetics may account for the different physiological effects of T and DHT. Androgen binding results in an at least 6-fold increase in androgen receptor stability.
|