Transcrocetin
Crocetin, also known as Transcrocetin, is a natural apocarotenoid dicarboxylic acid that is found in the crocus flower and Gardenia jasminoides (fruits). Crocetin is also anticarcinogenic, antineoplastic, antioxidant and protective agent. It forms brick red crystals with a melting point of 285 °C. Crocetin protects ultraviolet A-induced oxidative stress and cell death in skin in vitro and in vivo. Crocetin protects against hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats. Crocin and crocetin may provide neuroprotection in rats by reducing the production of various neurotoxic molecules, based on an in-vitro cell study.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1232 |
| CAS # | 27876-94-4 (free acid) |
| Pricing | Customizable size, Inquiry |
| Synonym | Crotecin, Trans-crocetin; Transcrocetin; TSC; NSC 407300; Natural Yellow 6; 8,8'-Diapocarotenedioic acid. ,8'-Diapo-psi,psi-carotenedioic acid. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C20H24O4 |
| Exact Mass | 328.1675 |
| Molecular Weight | 328.408 |
| Elemental Analysis | C, 73.15; H, 7.37; O, 19.49 |
| IUPAC/Chemical Name | (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioic acid |
| InChi Key | PANKHBYNKQNAHN-MQQNZMFNSA-N |
| InChi Code | InChI=1S/C20H24O4/c1-15(11-7-13-17(3)19(21)22)9-5-6-10-16(2)12-8-14-18(4)20(23)24/h5-14H,1-4H3,(H,21,22)(H,23,24)/b6-5+,11-7+,12-8+,15-9+,16-10+,17-13+,18-14+ |
| SMILES Code | O=C(O)/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C(O)=O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |