ZLDI-8
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-123931-5 mg |
| CAS # | 667880-38-8 |
| Pricing | 5 mg, USD $350.0 |
| Biological Activity | ZLDI-8 is a Notch activating/cleaving enzyme ADAM-17 inhibitor and inhibits the cleavage of Notch protein. ZLDI-8 decreases the expression of pro-survival/anti-apoptosis and epithelial-mesenchymal transition (EMT) related proteins. ZLDI-8 is also a competitive and irreversible tyrosine phosphatase (Lyp) inhibitor with an IC50 of 31.6 μM and a Ki of 26.22 μM. ZLDI-8 inhibits the growth of MHCC97-H cells with an IC50 of 5.32 μM[1][2]. |
| Purity | 98.53% |
| MWt | 433.52 |
| Formula | C₂₄H₂₃N₃O₃S |