Framycetin
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-17624-10 mg (16.27 mM * 1 mL in 0.9% NaCl) |
| CAS # | 119-04-0 |
| Pricing | 10 mg (16.27 mM * 1 mL in 0.9% NaCl), USD $84.0 |
| Biological Activity | Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections[1][2]. |
| Synonyms | Neomycin B; Fradiomycin B |
| MWt | 614.64 |
| Formula | C₂₃H₄₆N₆O₁₃ |