Framycetin

Supplier MedChemExpress
Product # HY-17624-10 mg (16.27 mM * 1 mL in 0.9% NaCl)
CAS # 119-04-0
Pricing 10 mg (16.27 mM * 1 mL in 0.9% NaCl), USD $84.0
Biological Activity Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections[1][2].
Synonyms Neomycin B; Fradiomycin B
MWt 614.64
Formula C₂₃H₄₆N₆O₁₃
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