DM4-SPDP
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-126493-50 mg |
| CAS # | 2245698-48-8 |
| Pricing | 50 mg, USD $9195.0 |
| Biological Activity | DM4-SPDP is a drug-linker conjugate composed of a potent antitubulin agent DM4 and a linker SMCC to make antibody drug conjugate[1]. SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls[2][3]. |
| MWt | 981.57 |
| Formula | C₄₅H₆₁ClN₄O₁₄S₂ |