AKT-IN-3
AKT-IN-3 is a potent and orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-3 also shows good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK.
| Supplier | BOC Sciences |
|---|---|
| Product # | 2374740-21-1 |
| Pricing | Inquire |
| Cas | 2374740-21-1 |
| Molecular Weight | 526.36 |
| Molecular Formula | C23H23Cl2F2N5O3 |
| Canonical SMILES | CNC(=O)CC1CC(C(CN1)NC(=O)C2=CC(=C(O2)Cl)C3=C(C=NN3C)Cl)C4=CC(=C(C=C4)F)F |