LML-134
LML134 is an orally active and high selective Histamine 3 receptor (H3R) inverse agonist with Kis of 0.3 nM and 12 nM for hH3R cAMP and hH3R bdg. LML134 is potentially useful for the Clinical Treatment of Excessive Sleep Disorders.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1293 |
| CAS # | 1542135-76-1 |
| Pricing | Customizable size, Inquiry |
| Synonym | LML-134; LML 134; LML134; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C19H29N5O3 |
| Exact Mass | 375.227 |
| Molecular Weight | 375.473 |
| Elemental Analysis | C, 60.78; H, 7.79; N, 18.65; O, 12.78 |
| IUPAC/Chemical Name | 1-(1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)piperidin-4-yl 4-cyclobutylpiperazine-1-carboxylate |
| InChi Key | BVUJMFFRMZRNAT-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C19H29N5O3/c1-21-18(25)6-5-17(20-21)23-9-7-16(8-10-23)27-19(26)24-13-11-22(12-14-24)15-3-2-4-15/h5-6,15-16H,2-4,7-14H2,1H3 |
| SMILES Code | O=C(N1CCN(C2CCC2)CC1)OC3CCN(C(C=C4)=NN(C)C4=O)CC3 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >3 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |