DM4-SMe
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130082-5 mg |
| CAS # | 796073-68-2 |
| Pricing | 5 mg, USD $495.0 |
| Biological Activity | DM4-SMe is a metabolite of antibody-maytansin conjugates (AMCs) and a tubulin inhibitor, and also a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM4-SMe inhibits KB cells with an IC50 of 0.026 nM[1][2]. |
| Purity | ≥98.0% |
| MWt | 826.46 |
| Formula | C₃₉H₅₆ClN₃O₁₀S₂ |