Phenoxodiol
Supplier | MedChemExpress |
---|---|
Product # | HY-13721-10 mg |
CAS # | 81267-65-4 |
Pricing | 10 mg, USD $300.0 |
Synonyms | Idronoxil; Dehydroequol; Haginin E |
MWt | 240.25 |
Formula | C₁₅H₁₂O₃ |
Biological Activity | Phenoxodiol, a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis. This agent also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner[1][2]. |
Purity | ≥98.0% |