Phenoxodiol

Supplier MedChemExpress
Product # HY-13721-10 mg
CAS # 81267-65-4
Pricing 10 mg, USD $300.0
Synonyms Idronoxil; Dehydroequol; Haginin E
MWt 240.25
Formula C₁₅H₁₂O₃
Biological Activity Phenoxodiol, a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis. This agent also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner[1][2].
Purity ≥98.0%
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