YL0919

Supplier MedChemExpress
Product # HY-100769-5 mg
CAS # 1339058-04-6
Pricing 5 mg, USD $80.0
Biological Activity YL0919 is an orally active antidepressant agent with dual activity as a highly seletive 5-HT uptake blocker and an effective 5-HT1A receptor agonist (Ki=0.19 nM). YL0919 inhibits the uptake of [3H]-5-HT into rat cerebral cortical synaptosomes and HEK293 cells with IC50s of 1.78 nM and 1.93 nM, respectively. YL0919 shows remarkable antidepressant effects in animal models and has the poential for the investigation of depressive disorder[1].
Purity 99.77%
MWt 334.84
Formula C₁₈H₂₃ClN₂O₂
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